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PROTAC AR Degrader-4

Katalog-Nr.GC36981

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PROTAC AR Degrader-4 Chemische Struktur

Cas No.: 1351169-31-7

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

PROTAC AR Degrader-4 comprises a cIAP1 ligand binding group, a linker and an androgen receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].

[1]. Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.

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