GSK2578215A |
| Katalog-Nr.GC18049 |
GSK2578215A ist ein potenter und hochselektiver LRRK2-Inhibitor, der IC50-Werte von etwa 10 nM sowohl gegen Wildtyp-LRRK2 als auch gegen die G2019S-Mutante aufweist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1285515-21-0
Sample solution is provided at 25 µL, 10mM.
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GSK2578215A is a potent and highly selective LRRK2 inhibitor, which exhibits IC50s of around 10 nM against both wild-type LRRK2 and the G2019S mutant.
References:
[1]. Reith AD, et al. GSK2578215A; a potent and highly selective 2-arylmethyloxy-5-substitutent-N-arylbenzamide LRRK2 kinase inhibitor. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5625-9.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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