M8-B (hydrochloride) |
Katalog-Nr.GC18296 |
M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).
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Cas No.: 883976-12-3
Sample solution is provided at 25 µL, 10mM.
M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice.
Review for M8-B (hydrochloride)
Average Rating: 5
(Based on Reviews and 2 reference(s) in Google Scholar.)Review for M8-B (hydrochloride)
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