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ML230 (Synonyms: CID44640177)

Katalog-Nr.GC34672

ML230 (CID44640177; SID 88095709) ist ein selektiver Inhibitor des ATP-bindenden Kassettentransporters (ABC) ABCG2 und 36-fach selektiv fÜr ABCG2 gegenÜber ABCB1 mit EC50s-Werten von 0,13 μM bzw. 4,65 μM.

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ML230 Chemische Struktur

Cas No.: 1776055-05-0

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

ML230 (CID44640177; SID 88095709) is a selective inhibitor of ATP-binding cassette (ABC) transporter ABCG2, and 36-fold selective for ABCG2 over ABCB1 with EC50s values of 0.13 μM and 4.65 μM, respectively[1]. EC50: ABCG2 (0.13 μM)[1]

[1]. Strouse JJ, et al. Selective Efflux Inhibition of ATP-binding Cassette Sub-family G Member 2. Probe Reports from the NIH Molecular Libraries Program. November 30, 2010.

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