TY-51469 |
| Katalog-Nr.GC32004 |
TY-51469 ist ein Chymase-Inhibitor mit IC50-Werten fÜr Affen- und menschliche Chymasen von 0,4 bzw. 7,0 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 603987-59-3
Sample solution is provided at 25 µL, 10mM.
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TY-51469 is a chymase inhibitor with IC50s for simian and human chymases of 0.4 and 7.0 nM, respectively.
TY-51469 shows 100% stability in rat plasma at 40°C for as long as 1 hour[1]. TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice[2].
[1]. Takato H, et al. The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice. Expert Opinion on Therapeutic Targets Volume 15, 2011 - Issue 4.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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