ULK-101 |
Katalog-Nr.GC34315 |
ULK-101 ist ein potenter und selektiver ULK1-Inhibitor mit IC50-Werten von 1,6 nM und 30 nM fÜr ULK1 bzw. ULK2. ULK-101 unterdrÜckt die Autophagie und sensibilisiert Krebszellen fÜr NÄhrstoffstress.
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Cas No.: 2443816-45-1
Sample solution is provided at 25 µL, 10mM.
ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1.6 nM and 30 nM for ULK1 and ULK2 in vitro, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress[1].
[1]. Martin KR, et al. A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress. iScience. 2018 Oct 26;8:74-84.
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