Reversan (Synonyms: CBLC4H10) |
| Katalog-Nr.GC12523 |
MST-312 ist ein Telomerase-Inhibitor. MST-312 ist ein chemisch modifiziertes Derivat von GrÜntee-Epigallocatechingallat (EGCG). MST-312 kann fÜr die Erforschung von Krebs wie dem multiplen Myelom (MM) verwendet werden.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 313397-13-6
Sample solution is provided at 25 µL, 10mM.
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Reversan (CBLC4H10) is a potent and nontoxic multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (Pgp) inhibitor[1][2].
References:
[1]. Tivnan A, et al. Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme. Front Neurosci. 2015 Jun 16;9:218.
[2]. Burkhart CA, et al. Small-molecule multidrug resistance-associated protein 1 inhibitor reversan increases the therapeutic index of chemotherapy in mouse models of neuroblastoma. Cancer Res. 2009 Aug 15;69(16):6573-80.
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