RN 1747 |
Katalog-Nr.GC15346 |
RN 1747 ist ein selektiver TRPV4-Agonist der Kationenkanal-Subfamilie V (Transient Receptor Potential) mit EC50-Werten von 0,77 μM, 4,0 μM und 4,1 μM für hTRPV4, mTRPV4 bzw. rTRPV4.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1024448-59-6
Sample solution is provided at 25 µL, 10mM.
RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1].
References:
[1]. Vincent F, et al. Identification and characterization of novel TRPV4 modulators. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.
Average Rating: 5
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