Startseite>>(S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide

(S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide

Katalog-Nr.GC91259

Ein Homolog von DHEA

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(S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide Chemische Struktur

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1 mg
114,00 $
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5 mg
503,00 $
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10 mg
893,00 $
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Sample solution is provided at 25 µL, 10mM.

Description of (S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Docosahexaenoyl ethanolamide (DHEA) has potential signaling roles in cancer, inflammation, and neurological development and functioning.1,2,3,4 At least some of DHEA’s effects are mediated through cannabinoid (CB) receptors, while some NAEs also act as vanilloid receptor agonists and voltage-gated K+ channel blockers.5,1,4 (S)-(+)-Docosahexaenyl-2’-droxy-1’-propylamide is a homolog of DHEA, characterized by the addition of an (S)-β-metl group at the terminal ethanolamine carbon. A similar modification of arachidonoyl ethanolamide to produce S-2 methanandamide imparts higher affinity for the CB receptor.6 The psiological actions of this compound have not been evaluated.

Chemical Properties of (S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide

Cas No. SDF
Formula C25H39NO2 M.Wt 385.6
Löslichkeit DMF: 2 mg/ml,DMSO: 14 mg/ml,Ethanol: 14 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.5934 mL 12.9668 mL 25.9336 mL
5 mM 0.5187 mL 2.5934 mL 5.1867 mL
10 mM 0.2593 mL 1.2967 mL 2.5934 mL
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Berechnen

In vivo Formulation Calculator (Clear solution) of (S)-(+)-Docosahexaenyl-2'-Hydroxy-1'-Propylamide

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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