(S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide

Name: (S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide
Brand: GlpBio
SKU: GC91263
Availability: InStock
Rating: 5 (30 reviews)

Katalog-Nr.GC91263

Ein Homolog von LOEA

Products are for research use only. Not for human use. We do not sell to patients.

(S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide Chemische Struktur

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1 mg	114,00 $	Auf Lager
5 mg	503,00 $	Auf Lager
10 mg	893,00 $	Auf Lager

Tel：(909) 407-4943 Email: sales@glpbio.com

Kundenbewertungen

Basiert auf Kundenrezensionen.

Sample solution is provided at 25 µL, 10mM.

GlpBio Produkte in seriösen Veröffentlichungen zitiert

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610.7931 (2022): 366-372

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Description Chemical Properties Product Documents

Product Documents

Quality Control & SDS

View current batch:

Purity: >98.00%

N-Acyl ethanolamines (NAEs) have diverse biological actions that are strongly affected by the associated acyl group. Linoleoyl ethanolamide (LOEA) has potential signaling roles in aging and neurological functioning.^1,2 LOEA has a weak affinity for cannabinoid (CB) receptors (K_i = 10 and 25 μM for CB₁ and CB₂, respectively).³ It also inhibits fatty acid amide drolase (FAAH; K_i = 9 μM) and is drolyzed by FAAH, and inhibits voltage-gated K⁺ channels.^4,5,6 (S)-(−)-Linoleyl-1’-droxy-2’-propylamide is a homolog of LOEA, characterized by the addition of an (S)-α-metl group at the metlene carbon adjacent to the amide nitrogen. A similar modification of arachidonoyl ethanolamide to produce S-1 methanandamide results in a diminished affinity for the CB receptor but greatly improved metabolic stability to aminopeptidase drolysis.⁷ The psiological actions of this compound have not been evaluated.

Cas No.		SDF
Formula	C₂₁H₃₉NO₂	M.Wt	337.5
Löslichkeit	DMF: 11 mg/ml,DMSO: 5 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml	Storage	Store at -20°C
General tips	Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition	Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table

Prepare stock solution
		1 mg	5 mg	10 mg
	1 mM	2.963 mL	14.8148 mL	29.6296 mL
	5 mM	0.5926 mL	2.963 mL	5.9259 mL
	10 mM	0.2963 mL	1.4815 mL	2.963 mL

Molaritätsrechner
Verdünnung-Rechner
Molecular Weight Calculator

Berechnen

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal:μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Bewertungen

Review for (S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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(S)-(-)-Linoleyl-1'-Hydroxy-2'-Propylamide

Kundenbewertungen

GlpBio Citations

Bioactive Compounds Premium Provider

GlpBio Produkte in seriösen Veröffentlichungen zitiert

Product Documents

Quality Control & SDS

Complete Stock Solution Preparation Table

Molaritätsrechner

Verdünnung-Rechner

Molecular Weight Calculator

In vivo Formulation Calculator (Clear solution)

Bewertungen