SABA1 |
| Katalog-Nr.GC70903 |
SABA1 besitzt antibakterielle Eigenschaften gegen Pseudomonas aeruginosa und Escherichia coli, mit einem IC50 von 4,0 µM gegen E. coli ACC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 690681-65-3
Sample solution is provided at 25 µL, 10mM.
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SABA1 inhibits BC via an atypical mechanism. It binds in the biotin binding site in the presence of ADP and represents a potentially antibiotic used to combat the antibacterial resistance crisis[1].
References:
[1]. Matthew K Craft, et al. Mechanism of biotin carboxylase inhibition by ethyl 4-[[2-chloro-5-(phenylcarbamoyl)phenyl]sulphonylamino]benzoate. J Enzyme Inhib Med Chem. 2022 Dec;37(1):100-108.
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