Sacubitril sodium (Synonyms: Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696. Entresto.) |
| Katalog-Nr.GB62196 |
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 149690-05-1
Sample solution is provided at 25 µL, 10mM.
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Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
Review for Sacubitril sodium
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Sacubitril sodium
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