SAINT C-18 (Synonyms: SAINT-2,SAINT-7,SAINT-18,Synthetic Amphiphile INTeraction C-18) |
| Katalog-Nr.GC91556 |
SAINT C-18 is a cationic lipid that has been used in the formation of liposomes for the delivery of plasmid DNA, proteins, siRNA, and small molecules.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 187587-97-9
Sample solution is provided at 25 µL, 10mM.
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SAINT C-18 is a cationic lipid that has been used in the formation of liposomes for the delivery of plasmid DNA, proteins, siRNA, and small molecules.1,2,3,4 Complexes of SAINT C-18 with plasmid DNA encoding pigment epithelium-derived factor (PEDF) inhibit corneal neovascularization induced by complexes of SAINT C-18 with plasmid DNA encoding FGF2, also known as basic FGF, in rats.[2]
References:
[1].van der Woude, I., Wagenaar, A., Meekel, A.A.P., et al.Novel pyridinium surfactants for efficient, nontoxic in vitro gene deliveryProc. Natl. Acad. Sci. USA94(4)1160-1165(1997).
[2].Kuo, C.-N., Yang, L.-C., Yang, C.-T., et al.Inhibition of corneal neovascularization with plasmid pigment epithelium-derived factor (p-PEDF) delivered by synthetic amphiphile INTeraction-18 (SAINT-18) vector in an experimental model of rat corneal angiogenesisExp. Eye Res.89(5)678-685(2009).
[3].van der Gun, B.T.F., Monami, A., Laarmann, S., et al.Serum insensitive, intranuclear protein delivery by the multipurpose cationic lipid SAINT-2J. Control Release123(3)228-238(2007).
[4].Adrian, J.E., Morselt, H.W., Süss, R., et al.Targeted SAINT-O-Somes for improved intracellular delivery of siRNA and cytotoxic drugs into endothelial cellsJ. Control Release144(3)341-349(2010).
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