Sel-green |
Katalog-Nr.GC61587 |
Sel-green, eine selektive Selenol-Fluoreszenzsonde, wird angewendet, um den Sec-Gehalt im Selenoenzym Thioredoxin-Reduktase zu quantifizieren und endogenes Sec in lebenden HepG2-Zellen abzubilden.
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Cas No.: 1574299-37-8
Sample solution is provided at 25 µL, 10mM.
Sel-green, a selective selenol fluorescent probe, is applied to quantify the Sec content in the selenoenzyme thioredoxin reductase and image endogenous Sec in live HepG2 cells[1].
Sel-green displays >20-fold selectivity of Sec over DTT[1]. Sel-green is suitable for identifying the selenol species metabolized from various selenocompounds in cells, which helps to clarify the mechanism underlying the cytotoxicity of different selenocompounds[1].
[1]. Baoxin Zhang, et al. Selective selenol fluorescent probes: design, synthesis, structural determinants, and biological applications. J Am Chem Soc. 2015 Jan 21;137(2):757-69.
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