STOCK2S 26016 |
| Katalog-Nr.GC50206 |
STOCK2S 26016 ist ein WNK-Signalweg-Inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 332922-63-1
Sample solution is provided at 25 µL, 10mM.
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Lysine deficient protein kinase (WNK) signaling inhibitor (IC50 = 16 μM). Inhibits binding of WNK1 and WNK4 to SPAK and phosphorylation of downstream transporters, NKCC1 and NCC, in mouse vascular smooth muscle and distal convoluted tubule cell cultures exposed to hypotonic shock, respectively.
Mori et al (2013) Chemical library screening for WNK signalling inhibitors using fluorescence correlation spectroscopy. Biochem.J. 455 339 PMID:23981180
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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