TCN 237 dihydrochloride |
Katalog-Nr.GC11585 |
TCN 237 Dihydrochlorid ist ein potenter und NR2B-selektiver NMDA-Antagonist mit einem Ki von 0,85 nM; NR2B Ca2+-Einstrom IC50 betrÄgt 9,7 nM; keine AktivitÄten auf NR2A, NR2C, NR2D, hERG-Kanal und α1-adrenergen Rezeptor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 700878-19-9
Sample solution is provided at 25 µL, 10mM.
NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor.
References:
[1]. McCauley JA, et al. NR2B-selective N-methyl-D-aspartate antagonists: synthesis and evaluation of 5-substituted benzimidazoles. J Med Chem. 2004 Apr 8;47(8):2089-96.
Average Rating: 5
(Based on Reviews and 29 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *