TCS 2314 |
| Katalog-Nr.GC18025 |
TCS 2314 (Verbindung 3) ist ein oral aktiver und selektiver Antagonist des sehr spÄten Antigen-4 (VLA-4, α4β1, CD49d/CD29) mit einem IC50 von 4,4 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 317353-73-4
Sample solution is provided at 25 µL, 10mM.
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TCS 2314 (compound 3) is orally active and selective very late antigen-4 (VLA-4, α4β1, CD49d/CD29) antagonist with an IC50 of 4.4 nM[1].
References:
[1]. Muro F, et al. Discovery of trans-4-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl]acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist. J Med Chem. 2009 Dec 24;52(24):7974-92.
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