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TFEB activator 1 (Synonyms: GO-Y019, TFEB Activator 1)

Katalog-Nr.GC39530

TFEB-Aktivator 1 ist ein oral wirksamer, mTOR-unabhÄngiger Aktivator von TFEB.

Products are for research use only. Not for human use. We do not sell to patients.

TFEB activator 1 Chemische Struktur

Cas No.: 39777-61-2

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5mg
46,00 $
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10mg
70,00 $
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25mg
140,00 $
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50mg
245,00 $
Auf Lager
100mg
385,00 $
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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

TFEB activator 1 is an orally effective, mTOR-independent activator of TFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167 nM. TFEB activator 1 enhances autophagy without inhibiting the mTOR pathway and has the potential for neurodegenerative diseases treatment[1].

[1]. Song JX, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016 Aug 2;12(8):1372-89.

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