Thalidomide-NH-PEG8-Ts |
| Katalog-Nr.GC67506 |
Thalidomide-NH-PEG8-Ts ist ein synthetisiertes E3-Ligase-Ligand-Linker-Konjugat, das den Thalidomid-basierten Cereblon-Liganden und den 8-Einheiten-PEG-Linker enthält, die in der PROTAC-Technologie verwendet werden, wie z. B. IDO1 PROTAC-Abbaumittel.
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Cas No.: 2488761-07-3
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-NH-PEG8-Ts is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 8-unit PEG linker used in PROTAC technology, such as IDO1 PROTAC degrader [1].
[1]. Hu M, et al. Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1. Acta Pharm Sin B. 2020;10(10):1943-1953.
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