Tixagevimab |
| Katalog-Nr.GC72404 |
Tixagevimab (AZD8895) ist ein humaner monoklonaler Antikörper, der auf die SARS-CoV-2 Rezeptor Bindungsdomäne (RBD) abzielt.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2420564-02-7
Sample solution is provided at 25 µL, 10mM.
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Tixagevimab can be combined with Cilgavimab to form AZD7442. AZD7442 (2, 4 or 16 mg/kg, i.v.) results in a dose-dependent decrease in lung infection titres and viral RNA levels and a significant reduction in infection titers at the 16 mg/kg dose compared to animals at the 2 mg/kg dose in hamsters infected with strain G614 or in hamsters infected with the Omicron variant[2].
References:
[1]. Jinhui Dong, et al. Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail. Nat Microbiol. 2021 Oct;6(10):1233-1244.
[2]. Jean-Sélim DRIOUICH, et al. Activity of Tixagevimab/Cilgavimab against the Omicron variant of SARS-CoV-2 in a hamster model.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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