TNP (Synonyms: IP3K Inhibitor, IP6K Inhibitor) |
Katalog-Nr.GC17758 |
TNP ist ein zelldurchlÄssiger Inhibitor von IP6K1 und IP3K mit IC50-Werten von 0,55 μM bzw. 10,2 μM fÜr IP3K. TNP bindet an die ATP-Bindungsstellen beider Enzyme.
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Cas No.: 519178-28-0
Sample solution is provided at 25 µL, 10mM.
TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1].
References:
[1]. Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.
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