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TNP (Synonyms: IP3K Inhibitor, IP6K Inhibitor)

Katalog-Nr.GC17758

TNP ist ein zelldurchlÄssiger Inhibitor von IP6K1 und IP3K mit IC50-Werten von 0,55 μM bzw. 10,2 μM fÜr IP3K. TNP bindet an die ATP-Bindungsstellen beider Enzyme.

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TNP Chemische Struktur

Cas No.: 519178-28-0

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

TNP is a cell-permeable inhibitor of IP6K1 and IP3K, with IC50 values of 0.55 µM and 10.2 µM for IP3K, respectively. TNP binds to the ATP-binding sites of both enzymes[1].

References:
[1]. Chang YT, et al. Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chembiochem. 2002 Sep 2;3(9):897-901.

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