Tos-PEG2-NH2 (Synonyms: PROTAC Linker 27) |
| Katalog-Nr.GC61340 |
Tos-PEG2-NH2 (PROTAC-Linker 27) ist ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.
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Cas No.: 1246286-33-8
Sample solution is provided at 25 µL, 10mM.
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Tos-PEG2-NH2 (PROTAC Linker 27) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
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