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Triethylene glycol monobenzyl ether

Katalog-Nr.GC62172

Triethylenglycolmonobenzylether ist ein PEG-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.

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Triethylene glycol monobenzyl ether Chemische Struktur

Cas No.: 55489-58-2

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Triethylene glycol monobenzyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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