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Tripterifordin

Katalog-Nr.GC39111

Tripterifordin besitzt signifikante Anti-HIV-ReplikationsaktivitÄten in H9-Lymphozytenzellen mit einem EC50-Wert von jeweils 3100 nM.

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Tripterifordin Chemische Struktur

Cas No.: 139122-81-9

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1mg
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5mg
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Sample solution is provided at 25 µL, 10mM.

Description of Tripterifordin

Tripterifordin, isolated from the roots of Tripterygium wilfordii, possesses significant anti-HIV replication activities in H9 lymphocyte cells with an EC50 value of 3100 nM, respectively[1].

[1]. Kobayashi S, et al. Syntheses of (-)-Tripterifordin and (-)-Neotripterifordin from Stevioside.J Org Chem. 2018 Feb 2;83(3):1606-1613.

Chemical Properties of Tripterifordin

Cas No. 139122-81-9 SDF
Canonical SMILES C[C@@]12[C@]3([H])[C@@](COC1=O)(CCC2)[C@@]4([H])[C@]5(C[C@@]([C@](C)(O)C5)([H])CC4)CC3
Formula C20H30O3 M.Wt 318.45
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Tripterifordin

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1 mg 5 mg 10 mg
1 mM 3.1402 mL 15.7011 mL 31.4021 mL
5 mM 0.628 mL 3.1402 mL 6.2804 mL
10 mM 0.314 mL 1.5701 mL 3.1402 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 29 reference(s) in Google Scholar.)

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