UAA crosslinker 1 |
| Katalog-Nr.GC32461 |
UAA-Crosslinker 1-Hydrochlorid ist ein Amber-Codon, das fÜr den Einbau von nicht-kanonischen AminosÄuren (ncAAs) verwendet wird. Die ncAAs kÖnnen in vivo in Proteine eingebaut werden, indem man sich die promiskuitive AktivitÄt bestimmter Wildtyp- und manipulierter Aminoacyl-tRNA-Synthetasen zunutze macht.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1167421-25-1
Sample solution is provided at 25 µL, 10mM.
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UAA crosslinker 1 act as substrates for pylRS/tRNA pair that enable its incorporation into a target protein.
[1]. VanBrunt MP, et al. Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry. Bioconjug Chem. 2015 Nov 18;26(11):2249-60.
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