Velpatasvir (Synonyms: GS-5816) |
Katalog-Nr.GC19372 |
Velpatasvir (VEL, GS-5816) ist ein neuartiger pangenotypischer Hepatitis-C-Virus (HCV)-Nichtstrukturprotein-5A-(NS5A)-Inhibitor mit AktivitÄt gegen HCV-Replikons vom Genotyp 1 (GT1) bis GT6. Velpatasvir ist auch ein SARS-CoV 3CLpro-Inhibitor mit einem IC50 von 2,16 μM.
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Cas No.: 1377049-84-7
Sample solution is provided at 25 µL, 10mM.
Velpatasvir (VEL, GS-5816) is a novel pan-genotypic hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor with activity against genotype 1 (GT1) to GT6 HCV replicons.target: NS5A
References:
[1]. Lawitz EJ et al. Clinical Resistance to Velpatasvir (GS-5816), a Novel Pan-Genotypic Inhibitor of the Hepatitis C Virus NS5A Protein. Antimicrob Agents Chemother. 2016 Aug 22;60(9):5368-78.
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