X5050 |
| Katalog-Nr.GC62025 |
X5050 ist ein REST-Inhibitor mit einem EC50-Wert von 2,1 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2404756-81-4
Sample solution is provided at 25 µL, 10mM.
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X5050 is a REST inhibitor, with an EC50 of 2.1 μM[1].
X5050 (100 µM, 1 day) induces a dosedependent decrease in the REST isoform in protein level[1].
X5050 (2 x 2µl of 20 mM) is active in HD pathological context[1].
[1]. JÉrÉmie Charbord, et al. High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes. Stem Cells. 2013 Sep;31(9):1816-28.
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