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Y-27152

Katalog-Nr.GC16690

Y-27152, ein Prodrug des KATP (Kir6)-KanalÖffners Y-26763, ist ein langwirksamer K+-KanalÖffner mit weniger Tachykardie: blutdrucksenkende Wirkung bei hypertensiven Ratten und Hunden im Bewusstseinszustand.

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Y-27152 Chemische Struktur

Cas No.: 127408-30-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Y-27152, a prodrug of the KATP (Kir6) channel opener Y-26763, is a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state[1][2].

References:
[1]. Nakajima T, et al. Y-27152, a long-acting K+ channel opener with less tachycardia: antihypertensive effects in hypertensive rats and dogs in conscious state. J Pharmacol Exp Ther. 1992 May;261(2):730-6.
[2]. Fukunari A, et al. Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels. Eur J Pharmacol. 1997 Apr 4;323(2-3):197-204.

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