Diazaborine (Synonyms: Diazaborine compound 2b18, Pkf 84.474, Pkf 84474, Pkf-84474, SA-84474) |
| Catalog No.GC26454 |
Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit.
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Cas No.: 22959-81-5
Sample solution is provided at 25 µL, 10mM.
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Diazaborine inhibits maturation of rRNAs for the large ribosomal subunit. Diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1. Diazaborine treatment causes, within minutes, a rapid redistribution of the protein from the nucleolus to the periphery of the nucleus, which provides a possible explanation for the effect of diazaborine on rRNA processing.
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