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Diridavumab

Catalog No.GC72450

Diridavumab is a monoclonal anti-HA stalk antibody.

Products are for research use only. Not for human use. We do not sell to patients.

Diridavumab Chemical Structure

Cas No.: 1393659-46-5

Size Price Stock Qty
1 mg
$315.00
In stock
5 mg
$675.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Diridavumab is a monoclonal anti-HA stalk antibody. Diridavumab stabilizes the prefusion HA structure and prevents pH-dependent fusion of cellular and viral membranes in endosomes. Diridavumab can be used in research of H2 influenza virus.

Diridavumab (CR6261; 500 μg/mL) neutralized AA60 and Sw06 with 39.4 μg/mL and 176.8μg/mL, respectively[1].

Diridavumab (CR6261; 1.7-15 mg/kg; i.p.; BALB/c mice with H2 influenza virus) protects mice against lethal H2 influenza virus in a dose-dependent manner[1].

References:
[1]. Sutton TC, et, al. In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice. J Virol. 2017 Nov 30;91(24):e01603-17.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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