Disodium pyrophosphate (Synonyms: SAPP; Sodium acid pyrophosphate) |
Catalog No.GC66181 |
Disodium pyrophosphate (SAPP), a food additive, is an inorganic compound. Disodium pyrophosphate has potential hematotoxic and immunotoxic effects.
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Cas No.: 7758-16-9
Sample solution is provided at 25 µL, 10mM.
Disodium pyrophosphate (SAPP), a food additive, is an inorganic compound. Disodium pyrophosphate has potential hematotoxic and immunotoxic effects[1].
Disodium pyrophosphate (oral administration, 12.6 mg/kg) displays hematotoxic and immunotoxic effects with long-term exposure in rats[1].
Animal Model: | Adult Sprague-Dawley rats[1] |
Dosage: | 12.6 mg/kg |
Administration: | Oral administration |
Result: | Displayed significant leukopenic condition. Decreased in CD3 T-lymphocyte and CD20 Blymphocyte immunolabeling in rats. Downregulated of PPAR-α and PPAR-γ together with upregulation of TNF-α. |
Average Rating: 5
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