DPP-9 Inhibitor 42 (Synonyms: Dipeptidyl Peptidase 9 Inhibitor 42) |
| Catalog No.GC91782 |
DPP-9 inhibitor 42 is an inhibitor of dipeptidyl peptidase 9 (DDP-9; IC50 = 0.0034 µM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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DPP-9 inhibitor 42 is an inhibitor of dipeptidyl peptidase 9 (DDP-9; IC50 = 0.0034 µM).[1] It is selective for DDP-9 over DPP-8, DPP-4, DPP-2, fibroblast activation protein (FAP), and prolyl endopeptidase (IC50s = 0.6, >10, >5, 10, and >10 µM, respectively). DPP-9 inhibitor 42 (10 µM) induces lactate dehydrogenase (LDH) release from THP-1 acute monocytic and HL-60 promyeloblast leukemia cells.
References:
[1].Benramdane, S., De Loose, J., Filippi, N., et al.Highly selective inhibitors of dipeptidyl peptidase 9 (DPP9) derived from the clinically used DPP4-inhibitor vildagliptinJ. Med. Chem.66(18)12717-12738(2023).
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