FIPI hydrochloride |
Catalog No.GB40196 |
Phospholipase D (PLD) inhibitor (IC50 values of 20-25 nM for both PLD1 and PLD2) that rapidly blocks in vivo phosphatidic acid (PA) production with subnanomolar potency. FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, PIP2 availability, cell spreading, and chemotA1is, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1781834-93-2
Sample solution is provided at 25 µL, 10mM.
Phospholipase D (PLD) inhibitor (IC50 values of 20-25 nM for both PLD1 and PLD2) that rapidly blocks in vivo phosphatidic acid (PA) production with subnanomolar potency. FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, PIP2 availability, cell spreading, and chemotA1is, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.
Average Rating: 5
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