1,2,3,6,7,8-Hexachlorodibenzofuran |
| Catalog No.GC90939 |
Un dibenzofurane polychloré de type dioxine
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 57117-44-9
Sample solution is provided at 25 µL, 10mM.
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1,2,3,6,7,8-Hexachlorodibenzofuran is a dioxin-like polychlorinated dibenzofuran (PCDF).1 It induces expression of the genes encoding aryl drocarbon droxylase (AHH) and ethoxyresorufin-O-deetlase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively).2 It reduces weight, induces tmic atrop, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl droxylase in rats (ED50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively).3 It has been found in the soil near municipal waste incinerators, in freshwater fish, and in human breastmilk.1,4,5
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