2',3'-Dideoxyguanosine-5'-O-triphosphate (sodium salt) |
Catalog No.GC90805 |
Un inhibiteur de la transcriptase inverse
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
2',3'-Dideoxyguanosine-5'-O-triphosphate (ddGTP) is a reverse transcriptase inhibitor (Kis = 13 and 6.7 nM for the visna virus and HIV-1 enzymes, respectively).1,2 ddGTP has been used in the synthesis of oligonucleotides containing a terminal ddG that are resistant to cleavage by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exonuclease.3 ddGTP has also been used to terminate chain extension produced by the Taq polymerase in PCR assays.4
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