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2-Oxopropanoate-13C5 sodium

Catalog No.GC72574

2-Oxopropanoate-13C5 sodium est le 2-oxopropanoate de Sodium étiqueté 13C.

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2-Oxopropanoate-13C5 sodium Chemical Structure

Cas No.: 89196-78-1

Taille Prix Stock Qté
100 mg
559,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
2-Oxopropanoate-13C5 (sodium) is the 13C labeled Sodium 2-oxopropanoate[1]. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. S Nemoto, et al. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000 Oct;20(19):7311-8.
[3]. W Zhao, et al. Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. Free Radic Res. 2000 Jul33(1):23-30.

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