2GBI (Synonyms: 2-Guanidinobenzimidazole) |
| Catalog No.GB40069 |
2GBI (5418-95-1) is a selective and state-dependent blocker of voltage-gated proton channels (Hv1). 2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side. Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including inflammatory, cancer, bone resorption and neurodegenerative disease.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 5418-95-1
Sample solution is provided at 25 µL, 10mM.
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2GBI (5418-95-1) is a selective and state-dependent blocker of voltage-gated proton channels (Hv1). 2GBI blocks the channel by binding to the voltage-sensing domain from its intracellular side. Inhibition of Hv1 is a potentially new target of intervention in various pathophysiological processes including inflammatory, cancer, bone resorption and neurodegenerative disease.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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