(3-Carboxypropyl)trimethylammonium chloride |
| Catalog No.GC33797 |
Le chlorure de (3-carboxypropyl)triméthylammonium est une substance angiopathique produite comme métabolite intermédiaire par le microbiote intestinal qui se nourrit de carnitine dans la viande rouge alimentaire.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6249-56-5
Sample solution is provided at 25 µL, 10mM.
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(3-Carboxypropyl)trimethylammonium chloride is angiopathic substance produced as an intermediary metabolite by gut microbiota that feed on carnitine in dietary red meat.
(3-Carboxypropyl)trimethylammonium chloride is produced as an intermediary metabolite by gut microbes of L-Carnitine to TMAO[1]. (3-Carboxypropyl)trimethylammonium chloride is implicated in arteriosclerosis and long-term cardiovascular death[2].
[1]. Koeth RA, et al. γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO. Cell Metab. 2014 Nov 4;20(5):799-812. [2]. Susumu Ogawa, et al. The Dynamics of Carnitine, γ-butyrobetaine and Trimethylamine N-oxide in Diabetics and the Effects of Changes in Renal Function. Ogawa et al., J Nephrol Ren Dis 2017, 1:2
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