AD 0261 |
| Catalog No.GC30451 |
AD 0261 est un piégeur de radicaux qui affiche une forte action inhibitrice sur la génération de peroxydes lipidiques et d'anions superoxydes.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 145600-69-7
Sample solution is provided at 25 µL, 10mM.
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AD 0261 is a radical scavenger which displays strong inhibitory action on the generation of lipid peroxides and superoxide anions.
AD 0261 displays strong inhibitory action on the generation of lipid peroxides (IC50=0.022 μM) and superoxide anions (IC50= 0.9-4.0 μM). AD 0261 inhibits cytokine release and/or production from PHA-P-stimulated lymphocytes in a dose-dependent manner. AD 0261 inhibits all parameters which are indicative of lymphocyte activation with 50% inhibition being achieved in a range of 1-10 μM. AD 0261 suppresses ornithine decarboxylase activity, the IC50 value being around 1.0 μM[1].
[1]. M. Sugiura, et al. Effect of the novel radical scavenger AD0261 on lymphocyte activation. Information Research. Agents and Actions. August 1994, Volume 41, Supplement 2, pp C216-C218.
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