Adenosine-5'-O-(3-thiotriphosphate) (sodium salt) |
| Catalog No.GC90949 |
Un agoniste du récepteur P2Y11
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 88453-52-5
Sample solution is provided at 25 µL, 10mM.
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Adenosine-5'-O-(3-thiotriphosphate) (ATPγS) is an agonist of the purinergic P2Y11 receptor.1 It induces inositol phosphate accumulation in CHO-K1 cells expressing the human or canine P2Y11 receptor (EC50s = 1.2 and 19.3 µM, respectively). ATPγS (10 µM) inhibits Junin virus-induced increases in mRNA encoding bone morphogenetic protein 6 (BMP6) and reduces particle forming units (PFUs) in Junin virus-infected primary rat osteoblasts.2 It induces insulin secretion by MIN6 pancreatic β-cells when used at a concentration of 25 µM.3
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