Almokalant (H 234/09) |
| Catalog No.GC32673 |
Almokalant (H 234/09) est un médicament antiarythmique de classe III, agit comme un inhibiteur des canaux potassiques et inhibe une composante spécifique (Ikr) du courant redresseur retardé dépendant du temps K+.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 123955-10-2
Sample solution is provided at 25 µL, 10mM.
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Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current.
Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker, and inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current[1].
Almokalant (125 μmol/kg, p.o.) induces cardiovascular defects, orofacial clefts, and tail defects in pregnant rats, after administration on Day 11. Almokalant also causes in pregnant rats[1].
[1]. Wellfelt K, et al. Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species. Reprod Toxicol. 1999 Mar-Apr;13(2):93-101.
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