Alpha-Lipoic Acid Choline Ester (Synonyms: EV-06; EV06; EV 06; alpha-LACE; alphaLACE; alpha LACE; UNR844; UNR-844; UNR 844; Alpha-Lipoic Acid Choline Ester;) |
Catalog No.GB62240 |
Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia.
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Cas No.: 1808266-58-1
Sample solution is provided at 25 µL, 10mM.
Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia. Alpha-LACE was designed to permeate biological membranes with the incorporation of the cationic choline head group. While lipoic acid does not permeate the cornea, the choline ester derivative of lipoic acid permeates the cornea, is hydrolyzed by corneal esterases and is transformed into the biologically active lipoic acid. LACE has been formulated into an ophthalmic solution to be applied twice daily as an eye-drop to treat presbyopia.
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