Asperfuran (Synonyms: (-)-Asperfuran) |
| Catalog No.GC46089 |
L'asperfurane est un dérivé antifongique du dihydrobenzofurane produit par une souche d'Aspergillus oryzae.
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Cas No.: 129277-10-7
Sample solution is provided at 25 µL, 10mM.
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Asperfuran is a fungal metabolite originally isolated from A. oryzae that has antifungal and anticancer activities.1 It inhibits the growth of 23 fungi in a disc assay when used at a concentration of 50 μg per disc. Asperfuran inhibits chitin synthase with an IC50 value of 300 μM. It inhibits proliferation of HeLa S3 and L1210 cancer cells (IC50s = 25 μg/ml for both).
|1. Pfefferle, W., Anke, H., Bross, M., et al. Asperfuran, a novel antifungal metabolite from Aspergillus oryzae. J. Antibiot. (Tokyo) 43(6), 648-654 (1990).
Average Rating: 5 (Based on Reviews and 36 reference(s) in Google Scholar.)
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