AUTEN-67 |
| Catalog No.GC70444 |
AUTEN-67 (Autophagy Enhancer - 67) est un activateur autophagique actif par voie orale et un inhibiteur de mtmr14.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1783800-77-0
Sample solution is provided at 25 µL, 10mM.
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AUTEN-67 (2-100 µM, 3 h) inhibits MTMR14 by nearly 3%-70%, induces autophagic flux, and promotes the survival in HeLa cells[1].
AUTEN-67 (10-100 µM, 2 h) induces autophagy in Drosophila via inhibiting EDTP[1].
AUTEN-67 (1-50 µM) decreases levels of LC3B-II, and protects neurons from oxidative stress (increases cell viability) in murine primary neurons[1].
AUTEN-67 enhances autophagy in zebrafish (10, 50 µM)and mice (e 50 µmol/g body weight, i.p.)[1].
AUTEN-67 (19 mg/kg, p.o., 3 times a week, for 3 month) restores nesting behavior and decreases APP level in the Alzheimer disease mice model[1].
References:
[1]. Papp D, et al. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Autophagy. 2016;12(2):273-86.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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