Accueil>>Signaling Pathways>> DNA Damage/DNA Repair>> DNA Alkylator/Crosslinker>>Bendamustine D4 (SDX-105 D4)

Bendamustine D4 (SDX-105 D4)

Catalog No.GC34305

Products are for research use only. Not for human use. We do not sell to patients.

Bendamustine D4 (SDX-105 D4) Chemical Structure

Taille Prix Stock Qté
1mg
202,00 $US
En stock
5mg
607,00 $US
En stock
10mg
1 103,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description of Bendamustine D4 (SDX-105 D4)

Bendamustine D4 is the deuterium labeled Bendamustine. Bendamustine is a DNA cross-linking agent that causes DNA breaks, with alkylating and antimetabolite properties.

Chemical Properties of Bendamustine D4 (SDX-105 D4)

Cas No. SDF
Canonical SMILES O=C(O)CCCC1=NC2=CC(N(CCCl)C([2H])([2H])C([2H])([2H])Cl)=CC=C2N1C
Formula C16H17D4Cl2N3O2 M.Wt 362.29
Solubility Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Bendamustine D4 (SDX-105 D4)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.7602 mL 13.8011 mL 27.6022 mL
5 mM 0.552 mL 2.7602 mL 5.5204 mL
10 mM 0.276 mL 1.3801 mL 2.7602 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Bendamustine D4 (SDX-105 D4)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Bendamustine D4 (SDX-105 D4)

Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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