BMS-8 |
Catalog No.GC42957 |
BMS-8 inhibe l'interaction PD-1/PD-L1 avec IC50 de 7,2 μM. BMS-8, se lie directement À PD-L1 et induit la formation d'homodimères PD-L1, qui À son tour empêche l'interaction avec PD-1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1675201-90-7
Sample solution is provided at 25 µL, 10mM.
BMS-8 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.
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