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Bocconoline

Catalog No.GC71116

Bocconoline est un puissant inhibiteur précoce de l'antigène endosomal 1 (eea1).

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Bocconoline Chemical Structure

Cas No.: 32906-88-0

Taille Prix Stock Qté
1 mg
459,00 $US
En stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD).

Bocconoline (compound 3) (30 μM; 24 h; hONS cells) affects primarily on EEA1 marker intensity in the cytoplasm, mitochondria marker intensity in inner region of the cytoplasm and microtubule-associated protein light chain 3B (LC3b) marker intensity in inner region of cytoplasm[1].

References:
[1]. Nguyen DT, et al. Chemical constituents from Macleaya cordata (Willd) R. Br. and their phenotypic functions against a Parkinson's disease patient-derived cell line. Bioorg Med Chem. 2020 Nov 1;28(21):115732.

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