ChemR23-IN-1 |
Catalog No.GC70594 |
ChemR23-IN-1 (composé 2) est un inhibiteur de chemr23 avec une CI50 de 38 nm pour chemr23 humain et de 100 nm pour chemr23 murin.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2378640-10-7
Sample solution is provided at 25 µL, 10mM.
ChemR23-IN-1 (compound 2) is a ChemR23 inhibitor with IC50s of 38 nM and 100 nM for human and mouse ChemR23, respectively. ChemR23-IN-1 inhibits chemotaxis of CAL-1 triggered by Chemerin in vitro.
References:
[1]. Takamichi Imaizumi, et al. The design, synthesis and evaluation of 2-aminobenzoxazole analogues as potent and orally efficacious ChemR23 inhibitors. Bioorg Med Chem. 2020 Sep 1;28(17):115622.
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