Cixutumumab (Synonyms: IMC-A12; NSC742460) |
Catalog No.GC68874 |
Cixutumumab (IMC-A12) is a humanized monoclonal antibody with high affinity for IGF-1R, which inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab has broad-spectrum anti-tumor activity and can be used in the study of cancers such as lung cancer, malignant tumors, leukemia, non-small cell lung cancer, and prostate cancer.
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Cas No.: 947687-12-9
Sample solution is provided at 25 µL, 10mM.
Average Rating: 5
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