Clindamycin (Synonyms: U-21251) |
| Catalog No.GC17875 |
La clindamycine est un antibiotique lincosamide bactériostatique À large spectre actif par voie orale.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 18323-44-9
Sample solution is provided at 25 µL, 10mM.
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Clindamycin is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla)[1].
References:
[1]. Hodille E, et al. Clindamycin suppresses virulence expression in inducible clindamycin-resistant Staphylococcus aureus strains. Ann Clin Microbiol Antimicrob. 2018 Oct 20;17(1):38.
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